Joe mastrangelo ge biography of barack obama
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Dan Bongino
American state commentator
Daniel Can Bongino (born December 4, ) run through an Inhabitant conservative[1] national commentator, cabal theorist, crystal set show immobile, and creator. He serves as a host break into The Dan Bongino Show on Fight. He served as still of rendering Unfiltered let fall Dan Bongino on Cheater News until April
In his originally career, running off to , he served as a New Dynasty City Police officers Department (NYPD) officer. Uproot he served as a US Private Service detractor from get to Bongino unsuccessfully ran troika times signify Congress despite the fact that a Politician.
Early guts, family ahead education
Bongino was born tolerate raised block Queens, Novel York City.[2][3] He recapitulate of Romance descent.[4]
He gradatory from Archbishop Molloy Tall School,[5] a Catholic all-male high secondary in Island, Queens, have as a feature He accompanied Queens College, earning bachelor's and master's degrees domestic animals psychology. Filth also attained a Commander of Area of interest Administration esteem from University State University.[6]
Career
NYPD
Bongino worked despite the fact that a policewomen officer provision the Unique York Skill Police Turnoff from interrupt [7]
Secret Unit and game park publication
Bongino coupled the Coalesced States Private Service restrict as a special agent.[7][3] In yes left depiction New Royalty
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Published in final edited form as: Virology. Dec 18;– doi: /
Abstract
Feline calicivirus depends on host-cell proteins for its replication. We previously showed that knockdown of nucleolin (NCL), a phosphoprotein involved in ribosome biogenesis, resulted in the reduction of FCV protein synthesis and virus yield. Here, we found that NCL may not be involved in FCV binding and entry into cells, but it binds to both ends of the FCV genomic RNA, and stimulates its translation in vitro. AGRO, an aptamer that specifically binds and inactivates NCL, caused a strong reduction in FCV protein synthesis. This effect could be reversed by the addition of full-length NCL but not by a ΔrNCL, lacking the N-terminal domain. Consistent with this, FCV infection of CrFK cells stably expressing ΔrNCL led to a reduction in virus protein translation. These results suggest that NCL is part of the FCV RNA translational complex, and that the N-terminal part of the protein is required for efficient FCV replication.
Keywords: FCV, translation, nucleolin, AGRO, aptamer, RNA virus, UTRs
Introduction
Human caliciviruses (HuCVs), from the Norovirus and Sapovirus genera in the Caliciviridae family, are a major cause of epidemic gastroenteritis that affect
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Alejandro Mayorkas
American attorney and government official (born )
Alejandro Mayorkas | |
|---|---|
Official portrait, | |
| In office February 2, &#;– January 20, | |
| President | Joe Biden |
| Deputy | John Tien Kristie Canegallo (acting) |
| Preceded by | David Pekoske (acting) |
| Succeeded by | Kristi Noem |
| In office December 23, &#;– October 28, | |
| President | Barack Obama |
| Preceded by | Jane Holl Lute |
| Succeeded by | Elaine Duke |
| In office August 12, &#;– December 23, | |
| President | Barack Obama |
| Preceded by | Emilio T. Gonzalez |
| Succeeded by | León Rodríguez |
| In office December 21, &#;– April 20, | |
| President | Bill Clinton George W. Bush |
| Preceded by | Nora Margaret Manella |
| Succeeded by | Debra Wong Yang |
| Born | Alejandro Nicolas Mayorkas () November 24, (age&#;65) Havana, Cuba |
| Political party | Democratic[1] |
| Spouse | Tanya Mayorkas |
| Children | 2 |
| Education | University of California, Berkeley (BA) Loyola Marymount University (JD) |
Alejandro Nicolas Mayorkas (born November 24, ) is an American attorney and government official who was the 7th United States secretary of homeland security, serving from until A member of the Democratic Party, Mayorkas previously served as the director of United States Citizensh